UR Code Q & A

UR Code Marker Q & A

1) What is the UR Code Process?

a) The patient being tested checks in with "receptionist or nurse" at Physician’s office

b) The "receptionist or nurse" opens a UR Code bottle that contains one pill per bottle (or 25ml of liquid) and two bar code stickers

c) The "receptionist or nurse" sticks the bar code sticker on an empty urine specimen bottle and sets it aside and puts another sticker on the Urine Drug Test Requisition Form

d) The patient takes the UR Code pill with a drink of water (or drinks the UR Code liquid) under supervision (watched by the receptionist or nurse)

e) UR Code is absorbed, not metabolized in the patient and is quickly cleared through the kidneys

f) about 30 minutes later the receptionist or nurse calls the patient and gives him/her a urine specimen bottle and asks the patient to fill it; urine can be now collected without supervision

g) The patient returns the urine specimen to the receptionist or nurse, who packages the sample bottle with bar code sticker and patient ID number and sends it to Laboratory Partner for testing (receptionist or nurse also fills out a Laboratory Partners requisition form and identifies which drugs are to be tested)

h) Urine sample is passed through our Partners LC-MS/MS machine and an encrypted file is compared to the bar code sticker on the Urine Sample. LC-MS/MS looks for specific results verifying that the sample bar code in the urine matches that of the actual donor

2) What are the Methods of UR Code Marker Manipulation?

a) CORRECT marker detected

b) WRONG Marker detected

c) NO Marker detected

d) DILUTED Marker detected

3) Attempts to manipulate the sample will occur, however, it is very clear on how manipulation attempts may be carried out. One can conclude that the:

a) "CORRECT marker detected", correct marker was detected by LC-MS/MS testing

b) "WRONG marker detected", a marker other than what was given to the patient was detected indicating urine was swapped with another sample

c) “NO marker detected” result was urine substituted in the bathroom after a marker was ingested

d) “DILUTED marker" detected” resulted from placing negative urine in the bladder or by mixing in the sample with clean urine or by over hydration

With over 5,000,000 UR Code tested thus far, the data clearly shows that using a detection urine marker eliminates the possibility of introducing a false negative urine sample regardless of the type. Missing marker, marker concentration low, and wrong marker are methods of manipulation that observed collections would not pick up; they would just be presented as negative urine. Only when a UR Code marker is presented will this data be captured.

4) What does UR Code consist of?

UR Code offers different combinations of polyethylene glycols in the form of a soft gel capsule as a urine identifier. Up to 1024 combinations are possible.

The individual UR Code capsules differ in the number of repetition units and are of different molecular weights and chain lengths.

5) What are Polyethylene Glycols?

Polyethylene Glycols are often used in manufacturing and can be found in virtually all drug groups including tablets that are cleared for use for children. They are also used in sedatives, relaxants, painkillers and other substances.

The polyethylene glycols used for the UR Code are absorbed, not metabolized and quickly cleared through the kidneys. They are therefore excreted in their entirety and do not have nutritional value.

6) Is UR Code a drug?

No. UR Code is not considered a drug, it is an inert substance.

UR Code is not used in the diagnosis, cure, mitigation, treatment, or prevention of disease and it does not affect the structure or any function of the body.

7) Does UR Code have side effects?

No. Polyethylene glycols have been used for more than 50 years as a galenic basis (in order to enhance absorption) for drugs and are considered an 'inactive ingredient by the FDA. In over 5,000,000 UR Code doses administered no side effects have been observed or reported.

8) How long does it take until the UR Code is completely excreted?

Usually, UR Code is completely excreted after six to eight hours. Should the patient not urinate during that time, it may be possible to find UR Code in the urine at an even later time.

9) How is UR Code stored?

It may be stored at room temperature in its packaging.

10) What is the shelf life of UR Code?

5 years at room temperature, much longer if refrigerated.